The AMR Accelerator

The AMR Accelerator, with its broad scope and unified structure, is addressing the diverse scientific challenges of AMR. The critical challenge is to develop a robust pipeline of new antimicrobial medicines. This is necessary to counter the resistance that will most likely continue to develop even against new drugs. A successful AMR Accelerator will make a significant contribution to reducing the morbidity and mortality associated with antibiotic-resistant bacterial infections, in Europe and worldwide.

It is imperative that the AMR Accelerator speaks with a single voice to the community of stakeholders, and that the synergies between the individual projects are identified and exploited. The management structure of the AMR Accelerator should support these overarching goals.

The Coordination and Support Office (CSO) oversees the day-to-day work in COMBINE and is responsible for coordinating support to the Accelerator projects via the Coordination Committee, the Data Management Group, and the Communication and Ethics Advisory Boards.

The Coordination Committee (CC) is composed of key representatives nominated by each AMR Accelerator project and led by the COMBINE CSO. In this forum the CSO coordinates support for projects across the AMR Accelerator and identifies and implements synergies between individual projects.

The Data Management Group (DMG) is composed of Data Management Champions from each Accelerator project. The DMG streamlines data governance in the projects and oversees the implementation of FAIR processes and software tools to support the day-to-day operation of individual AMR Accelerator projects.

The Ethics Advisory Board (EAB) advises COMBINE on ethical issues relating to animal experimentation, clinical studies and data management, and also acts as an advisory board to individual AMR Accelerator partner projects on request.

The Communication Advisory Board (CAB) consists of independent external members and its objectives are (i) to support the exchange of news, information and data between the AMR Accelerator and the community of stakeholders in the AMR field, (ii) to explore the potential for synergies and collaboration with other initiatives on AMR, and (iii) contribute to coordinating an AMR strategy on a global scale.