This webinar will provide an overview of animal infection models commonly used for studies of antibiotics against gram-negative bacteria. The webinar is driven by the COMBINE objective to harmonize and standardize a protocol for a mouse infection model used for efficacy and PKPD studies. The infection model will be validated through well-characterized bacterial strains and control compounds in different animal labs. During the webinar we would like to initiate a discussion on pro’s and con’s of various procedures and animal models, aiming to guide which animal infection model COMBINE should focus on.

For additional information about the webinar, please contact Jennifer Hoover (Jennifer.L.Hoover@gsk.com) or Lena Friberg (lena.friberg@farmaci.uu.se).

Speakers:

Sylvie Sordello, COMBINE WP5 and Evotec
Jon Hansen, COMBINE WP5 and Statens Serum Institut
Jennifer Hoover, COMBINE WP5 and GlaxoSmithKline